A 54-yo man with mild HTN on no meds c/o of dysarthria, trouble with swallowing and moving his tongue. Neuro exam was normal except for left-side tongue deviation. Blood work excluded infection or immune disorders. An MRI was performed. What is it?
Carotid artery dissection
Complicated migraine
Acute cerebral vascular occlusion
Multiple sclerosis
Subarachnoid hemorrhage
You are correct. MRI showed carotid artery dissection, without abnormal signal in the hypoglossal nerve. Isolated hypoglossal nerve palsy is associated with lesions of the peripheral segment rather than at the brainstem origin. The hypoglossal nerve passes between the carotid artery and the internal jugular vein. In one series, >5% of patients with internal carotid artery dissection presented with isolated hypoglossal nerve involvement. This patient was treated with antihypertensive and antiplatelet medication. Symptoms improved by 3 weeks after admission.
(BMJ) - A 19-yo man with no PMHx had a chest tube placed for a large spontaneous pneumothorax. Symptoms initially improved, but soon he began coughing up frothy, clear, yellow, sputum and developed respiratory distress. X-ray was repeated. What is the diagnosis?
Atypical pneumonia
Lung abscess
Chest tube malfunction
Reexpansion pulmonary edema
Pulmonary hemorrhage
You are correct. Reexpansion pulmonary edema is a complication of drainage of pleural effusions and pneumothoraces. Large volume, clear (not bloody) sputum is common. X-ray reveals unilateral diffuse airspace opacification of the reinflated lung with the chest tube in place. Management is supportive. The use of diuretics for the condition is controversial. This patient rapidly improved with high-flow O2, morphine, and furosemide; he was discharged 2 days later.
(BMJ) - A 74-yo man with no past medical Hx c/o pain and blisters on his right hand several hours after playing hockey. There was no trauma to his hands. He had no fever or other symptoms. What is the diagnosis?
Blistering distal dactylitis
Herpes zoster
Flexor tenosynovitis
Frostbite
Allergic reaction
You are correct. Blistering distal dactylitis is a superficial bacterial infection of the anterior fat pad, typically caused by gram-positive organisms. It presents with large blisters or bullae affecting multiple fingers. His clinicians hypothesized that lacing up hockey skates may have caused superficial microtrauma to the hands, predisposing to potential infection. Moist, infrequently washed hockey equipment may have harbored infectious organisms. He improved after 10 days of oral cephalexin, blister debridement via lateral puncture, and silver sulfadiazine dressings.
(BMJ) - A 40-yo man c/o nasal blockage x 11 yrs, anosmia, and “something coming out of my nose.” Hx includes hay fever and aspirin intolerance. Exam revealed bilateral glistening fleshy structures in his nose, left worse than right. What is the diagnosis?
Deviated septum
Nasal foreign body
Rhabdomyosarcoma
Gross nasal polyps
Septal hematoma
You are correct. Nasal polyps, a benign inflammation of the nasal sinus mucosa, are a common cause of nasal obstruction and often result from chronic rhinosinusitis. Initial treatment is with topical steroids. This patient did not respond to steroids; nasal polypectomy was performed.
A healthy 84-yo woman had 3 mo of double vision, droopy eyelids (worse on the right and in evening), and progressive bilateral arm weakness that was worse on exertion and better after rest. Cognition, reflexes, and sensation were normal. Diagnosis?
Botulism
Guillain-Barre syndrome
Posterior circulation stroke
Myasthenia gravis
Cavernous sinus thrombosis
You are correct. The autoimmune disease myasthenia gravis often presents with bilateral complex external ophthalmoplegia. Symptoms are often worse in the evening and after exertion. Long tract signs, sensory symptoms, and headache are absent. Diagnosis is confirmed with IV edrophonium test. This patient improved with the usual treatment of anticholinesterase drugs and corticosteroids.
(BMJ) - A healthy 22-yo woman presented with painful genital ulcers for 1 year, unresponsive to various treatments. Exam revealed labia majora and cervix lesions, aphthous-like oral lesions, and leg folliculitis. ESR was elevated. What is the diagnosis?
Herpes zoster
Disseminated gonorrhea
Systemic lupus erythematosus
Ulcerative colitis
Behcet disease
You are correct. She meets criteria for Behcet disease: recurrent oral ulcers with 2 of these 4: recurrent genital ulcerations, eye lesions (uveitis or retinal vasculitis), skin lesions (erythema nodosum or folliculitis), positive pathergy test (a small red bump or sterile pustule after an intracutaneous insult). Most common along the Old Silk Road from the Far East to the Mediterranean, the condition was named after Turkish dermatologist Hulusi Behcet. The patient improved on corticosteroids and colchicine.
A 45-yo man presented with a 6-mo hx of diarrhea, abdominal pain, weight loss, and iron-deficiency anemia. Extensive work-up including stool studies, UGI, and limited colonoscopy was negative. Abdominal US and capsule endoscopy were performed. Diagnosis?
Whipworms (Trichuris trichiura)
Yersinia enterocolitica
Meckel diverticulum
Cecal malignancy
H pylori infection
You are correct. Capsule endoscopy revealed whipworms, Trichuris trichiura, a major nematode species affecting the human bowel, in the ileocecal valve. Ultrasound findings of thickened ileal wall and fluid-filled loops are not pathognomonic, but in the clinical context raise the suspicion of a malabsorption condition. The patient recovered rapidly with a course of mebendazole and short-term iron supplementation.
A 6-yo boy presents with 1 mo of itchy 1- to 3-mm pearly, dome-shaped papules in a red, scaly, and slightly edematous area on the thighs. He is healthy with no history of atopy. What is it?
Impetigo
Lichen planus
Herpes zoster
Scabies
Molluscum-associated dermatitis
You are correct. The image shows molluscum-associated dermatitis caused by the molluscipoxvirus. The small, pearly, dome-shaped papules with central umbilication favor intertriginous areas, although they may appear anywhere. Molluscum contagiosum infection may result in an associated dermatitis thought to be secondary to a delayed hypersensitivity reaction to the virus. The specific onset of dermatitis confined to the site of the molluscum favors the diagnosis of molluscum-associated dermatitis over atopic dermatitis. The condition is usually self-limited.