By rray, 12 February, 2015
By rray, 12 February, 2015
By rray, 12 February, 2015
By rray, 12 February, 2015
By whadikin, 12 February, 2015
(BMJ)—A 60-yo woman w/ DM and recurrent UTIs presented w/ a scaly rash on the soles of her feet x 4 mo and acute chest pain. ECG and echo: pericarditis. CT: inflamed, nonfunctioning left kidney w/ calculus. Rash and pericarditis resolved after nephrectomy. What is the diagnosis?
Olmsted syndrome
Ichthyosis vulgaris
Acquired palmoplantar keratoderma
Psoriasis
Pitted keratolysis
You are correct. Acquired palmoplantar keratoderma is characterized by abnormal thickening of the skin on the palms and soles. It is associated w/ malignancy, drugs, infections, and chronic systemic diseases. In this case, the pt had underlying xanthogranulomatous pyelonephritis. Tx is aimed at the underlying cause. Presentation w/ palmoplantar keratoderma should prompt search for systemic dz.