Discuss potential for risk-reduction benefits, adverse effects, drug interactions, pt preferences, etc., to inform tx decisions. If 10-yr AS-CVD risk ≥7.5% use mod or high-intensity [A]; mod-intensity reasonable if AS-CVD risk 5% to <7.5% [C]

¹² <b>Atorvastatin</b> 40 mg: evidence from 1 RCT only after down-titration from 80 mg due to intolerance. <br><br>
¹³ <b>Rosuvastatin</b> 40 mg not included in RCTs.
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¹⁴ Mod-intensity: Other FDA-approved options not included in RCTs: <b>atorvastatin</b> 20 mg, <b>rosuvastatin</b> 5 mg, <b>pravastatin</b> 80 mg, <b>fluvastatin</b> XL 80 mg, <b>pitavastatin</b> 2-4 mg. Although <b>simvastatin</b> 80 mg was studied, this dose is not FDA-recommended d/t myopathy risk.