High-intensity statin5,6 + lifestyle [B]

By vgreene, 19 May, 2015
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<sup>5</sup> If not high-intensity statin candidate, use mod-intensity tx like for >75 yo w/ AS-CVD. <br><br>
<sup>6</sup> It is reasonable to intensify statin tx to achieve at least a 50% LDL-C reduction [E]. After max statin intensity achieved, it is reasonable to add a nonstatin drug to further reduce LDL-C [E].
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<sup>7</sup> <b>Atorvastatin</b> 40 mg: evidence from 1 RCT only after down-titration from 80 mg due to intolerance.
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<sup>8</sup> <b>Rosuvastatin</b> 40 mg not included in RCTs.
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High-intensity statin<sup>5,6</sup> + lifestyle [B]