General population screening is controversial. GOLD advocates active case-finding, not screening spirometry

By vgreene, 6 November, 2014
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No
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<sup>1</sup> A1AT-deficiency pts typically present <45 yo w/ lower lobe emphysema.
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No data show that identifying pts before significant sx develop improves COPD outcomes or effectively directs management
If family member w/ A1AT1 deficiency: A1AT screening/counseling
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General population screening is controversial. GOLD advocates active case-finding, not screening spirometry