| Guideline | Resources |
| tPA in Ischemic Stroke: 2013 ACEP Clinical Policy | Epocrates Guideline Synopsis |
Key Points
Offer IV tPA to pts meeting criteria who can be treated w/in 3h of sx onset, and consider if w/in 4.5h of sx onset.
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American College of Emergency Physicians. Clinical Policy: Use of Intravenous tPA for the Management of Acute Ischemic Stroke in the Emergency Department. Ann Emerg Med. 2013;61:225–243.
Epocrates Guideline Synopsis Last Update:
Dec 29, 2016
Publication Year:
2013
Source:
ACEP
- American College of Emergency Physicians
Endorsed By:
American Academy of Neurology
Evidence Grade
| [A] | Accepted practice; based on supporting Class I studies and/or robust supporting Class II studies |
| [B] | May be acceptable; based on supporting Class II studies and/or robust supporting Class III studies |
| [C] | Requires further investigation; no adequate supporting Class I or II studies |
Abbreviations
| DM | diabetes mellitus |
| GI | gastrointestinal |
| GU | genitourinary |
| IV | intravenous |
| MCA | middle cerebral artery |
| NIHSS | National Institutes of Health Stroke Scale |
| SAH | subarachnoid hemorrhage |
| tPA | tissue plasminogen activator |
Evidence Grade
| A | = | Accepted practice; based on supporting Class I studies and/or robust supporting Class II studies |
| B | = | May be acceptable; based on supporting Class II studies and/or robust supporting Class III studies |
| C | = | Requires further investigation; no adequate supporting Class I or II studies |