May cause false positive result on amphetamines immunoassay

By rray, 4 April, 2024
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<sup>1</sup> Merigian KS, Browning RG. Desipramine and amantadine causing false-positive urine test for amphetamine. <i>Ann Emerg Med.</i> 1993 Dec;22(12):1927-8.
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<sup>2</sup> Kaplan J, et al. Case Reports of Aripiprazole Causing False-Positive Urine Amphetamine Drug Screens in Children. <i>Pediatrics.</i> 2015 Dec;136(6):e1625-8. <a href=https://pubmed.ncbi.nlm.nih.gov/26527556/><u>PubMed® abstract</u></a>
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<sup>3</sup> Fenderson JL, et al. Amphetamine positive urine toxicology screen secondary to atomoxetine. <i>Case Rep Psychiatry.</i> 2013:2013:381261. <a href=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570929/pdf/CRIM.PSYCHIATRY2013-381261.pdf><u>Free, full-text PDF</u></a>
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<sup>4</sup> Olsen KM, et al. Metabolites of chlorpromazine and brompheniramine may cause false-positive urine amphetamine results with monoclonal EMIT d.a.u. immunoassay. <i>Clin Chem.</i> 1992 Apr;38(4):611-2.
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<sup>5</sup> Wellbutrin SR. Prescribing information. GlaxoSmithKline; 2022.
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<sup>6</sup> Gomila I, et al. Cross-Reactivity of Chloroquine and Hydroxychloroquine With DRI Amphetamine Immunoassay. <i>Ther Drug Monit.</i> 2017 Apr;39(2): 192-196. <a href=https://pubmed.ncbi.nlm.nih.gov/28207572/><u>PubMed® abstract</u></a>
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<sup>7</sup> Pristiq. Prescribing information. Pfizer Inc; 2023.
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<sup>8</sup> Stout PR, et al. Evaluation of ephedrine, pseudoephedrine and phenylpropanolamine concentrations in human urine samples and a comparison of the specificity of DRI amphetamines and Abuscreen online (KIMS) amphetamines screening immunoassays. <i>J Forensic Sci.</i> 2004 Jan;49(1):160-4. <a href=https://pubmed.ncbi.nlm.nih.gov/14979364/><u>PubMed® abstract</u></a>
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<sup>9</sup> Labetalol. Prescribing information. Par Pharmaceutical, Inc; 2017.
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<sup>10</sup> Fucci N. False positive results for amphetamine in urine of a patient with diabetes mellitus. <i>Forensic Sci Int.</i> 2012 Nov 30;223(1-3):e60.
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<sup>11</sup> Manzi S, et al. Methylphenidate produces a false-positive urine amphetamine screen. <i>Pediatr Emerg Care.</i> 2002 Oct;18(5):401.
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<sup>12</sup> Moeller KE, et al. Clinical Interpretation of Urine Drug Tests: What Clinicians Need to Know About Urine Drug Screens. <i>Mayo Clin Proc.</i> 2017 May;92(5):774-796. <a href=https://www.mayoclinicproceedings.org/action/showPdf?pii=S0025-6196%2816%2930825-4><u>Free, full-text PDF</u></a>
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<sup>13</sup> Curtin LB, Cawley MJ. Immunoassay cross-reactivity of phenylephrine and methamphetamine. <i>Pharmacotherapy.</i> 2012 May;32(5):e98-102. <a href=https://pubmed.ncbi.nlm.nih.gov/22499397/><u>PubMed® abstract</u></a>
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<sup>14</sup> Melanson SEF, et al. Reduced interference by phenothiazines in amphetamine drug of abuse immunoassays. <i>Arch Pathol Lab Med.</i> 2006 Dec;130(12):1834-8. <a href=https://meridian.allenpress.com/aplm/article/130/12/1834/459751/Reduced-Interference-by-Phenothiazines-in><u>Free, full-text article</u></a>
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<sup>15</sup> Baron JM, et al. The trazodone metabolite meta-chlorophenylpiperazine can cause false-positive urine amphetamine immunoassay results. <i>J Anal Toxicol.</i> 2011 Jul;35(6):364-8. <a href=https://pubmed.ncbi.nlm.nih.gov/21740694/><u>PubMed® abstract</u></a>
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<sup>16</sup> Jones R, et al. Trimethobenzamide cross-reacts in immunoassays of amphetamine/methamphetamine. <i>Clin Chem.</i> 1993 Apr;39(4):699-700.
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<sup>17</sup> Effexor XR. Prescribing information. Viatris Inc; 2023.
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May cause false-positive result on amphetamines immunoassay: